DAP凋亡誘導蛋白激酶2抗體應用說明
2021-11-25 14:34 作者:洛辰 來源:上海遠慕生物試劑
英文名稱:DRAK2:
中文名稱:DAP凋亡誘導蛋白激酶2抗體:
別:名:DAP kinase related apoptosis inducing protein; DAP kinase related apoptosis inducing protein kinase 2; Death associated protein kinase related 2; DRAK 2; Serine/threonine kinase 17b (apoptosis inducing); Serine/threonine kinase 17b; Serine/threonine protein kinase 17B; STK17B; ST17B_HUMAN.:
研究領域:腫瘤 信號轉導 細胞凋亡 轉錄調節因子 激酶和磷酸酶:
抗體來源:Rabbit:
克隆類型:Polyclonal:
交叉反應:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,:
產品應用:ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.:
分 子 量:42kDa:
細胞定位:細胞核 細胞漿 細胞膜:
性:狀:Lyophilized or Liquid:
濃:度:1mg/ml:
免 疫 原:KLH conjugated synthetic peptide derived from human DRAK2:281-372/372:
亞:型:IgG:
純化方法:affinity purified by Protein A:
儲 存 液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.:
PubMed:PubMed:
產品介紹:Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK1 and RIP, are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 (for DAP kinase related apoptosis inducing protein kinases). DRAKs contain an N terminal kinase domain and a C terminal regulation domain. Overexpression of DRAK2 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK2 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues.: