英文名稱    Dynamin 3    

中文名稱    酶動力蛋白3抗體    

別    名    Dynamin III; testicular; DNM 3; DNM3; DNM3 protein; Dyn3; DYN3_HUMAN; Dyna III; DynaIII; dynamin 2; Dynamin; Dynamin family member; Dynamin testicular; Dynamin-3; Dynamin3; EC 3.6.5.5; KIAA0820; MGC70433; T dynamin; T-dynamin.    

供應(yīng)商 遠慕生物  

研究領(lǐng)域    細(xì)胞生物  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  細(xì)胞類型標(biāo)志物      

抗體來源    Rabbit    

克隆類型    Polyclonal    

交叉反應(yīng)    Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep,     

產(chǎn)品應(yīng)用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 酶動力蛋白3抗體（石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    98kDa    

細(xì)胞定位    細(xì)胞漿     

性    狀    Lyophilized or Liquid    

濃    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human Dynamin 3    

亞    型    IgG    

純化方法    affinity purified by Protein A    

儲 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存條件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

酶動力蛋白3抗體產(chǎn)品介紹    background:

Dynamin III is a microtubule-associated, force-producing GTPase that can form helical structures around the neck of vesicles. GTP hydrolysis-dependent extension of the helical structure releases the vesicle. Dynamin III contains a pair of phosphorylation sites at Ser 759 and Ser 763. Both 3.0 and 7.2 kb Dynamin III transcripts are detectable in brain. The 3.0 kb Dynamin III transcript is also detectable in testis. The 7.2 kb Dynamin III transcript is brain-specific for a protein thought to influence synaptogenesis in the CNS through recycling, neurotransmitter reuptake and growth factor-receptor signaling, in a thyroid hormone-dependent manner. A 6 kb antisense transcript (Dnm3os) contained within an intron of the mouse Dnm3 gene may be under transregulation by twist during mouse development. Dynamin III and Dnm3os transcripts overlap during embryogenesis and in adult tissues, except that Dynamin III is abundant in adult brain and testis whereas Dnm3os is abundant in embryos and gravid uterus.

Function:
Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis.

Subcellular Location:
Cytoplasm. Cytoplasm; cytoskeleton. Microtubule-associated.

Similarity:
Belongs to the dynamin family.
Contains 1 GED domain.
Contains 1 PH domain.