英文名稱    DACH2    

中文名稱    轉(zhuǎn)錄調(diào)節(jié)因子DACH2抗體    

別    名    DACH 2; dachshund 2; Dachshund homolog 2 (Drosophila); Dachshund homolog 2; Dachshund2; FLJ31391; HGNC:16814; MGC138545.    

供 應(yīng) 商    遠(yuǎn)慕生物      

研究領(lǐng)域    腫瘤  免疫學(xué)  轉(zhuǎn)錄調(diào)節(jié)因子      

抗體來源    Rabbit    

克隆類型    Polyclonal    

交叉反應(yīng)    Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,     

產(chǎn)品應(yīng)用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 轉(zhuǎn)錄調(diào)節(jié)因子DACH2抗體（石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    65kDa    

細(xì)胞定位    細(xì)胞核     

性    狀    Lyophilized or Liquid    

濃    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human DACH2    

亞    型    IgG    

純化方法    affinity purified by Protein A    

儲 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存條件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

轉(zhuǎn)錄調(diào)節(jié)因子DACH2抗體產(chǎn)品介紹    background:

DACH2 is a transcription factor that is involved in regulation of organogenesis. It seems to be a regulator for SIX1 and SIX6 and may act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter. It probably binds to DNA via its DACH box-N domain.

Subunit:
Interacts with SIX6 and EYA2.

Subcellular Location:
Nuclear.

Similarity:
Belongs to the DACH/dachshund family.

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.