中文名稱    嗜酸性粒細胞陽離子蛋白抗體    

英文名稱    EAR1    

別    名    ECP1_MOUSE; Cytotoxic ribonuclease; Eosinophil cationic protein 1; Eosinophil secondary granule ribonuclease 1; EAR-1; Ribonuclease 3-1; RNase 3-1; eosinophil cationic protein 1 precursor; Ear1; ECP 1.    

供 應 商    遠慕生物

研究領域    細胞生物  免疫學  通道蛋白      

抗體來源    Rabbit    

克隆類型    Polyclonal    

交叉反應    Mouse, Rat,     

產品應用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 嗜酸性粒細胞陽離子蛋白抗體（石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    14kDa    

細胞定位    分泌型蛋白     

性    狀    Lyophilized or Liquid    

濃    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from mouse Eosinophil cationic protein 1    

亞    型    IgG    

純化方法    affinity purified by Protein A    

儲 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存條件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

嗜酸性粒細胞陽離子蛋白抗體產品介紹    background:

Eosinophil derived neurotoxin (EDN) is a protein belonging to the ribonuclease (RNase) A superfamily. It has recently been found to have antiviral activity against respiratory syncytial virus and human immunodeficiency virus in vitro.

Function:
Cytotoxin and helminthotoxin with ribonuclease activity. Possesses a wide variety of biological activities.

Subunit:
Interacts with bacterial lipopolysaccharide (LPS) and lipoteichoic acid (LTA). In vitro interacts with and insert into lipid bilayers composed of dioleoyl phosphatidylcholine and dioleoyl phosphatidylglycerol. In vitro, tends to form amyloid-like aggregates at pH 3, but not at pH 5, nor 7.

Subcellular Location:
Secreted. Note=Located in the matrix of eosinophil large specific granule, which are released following activation by an immune stimulus.

Similarity:
Belongs to the pancreatic ribonuclease family.

Gene ID:
13586

Database links:
Entrez Gene: 13586 Mouse